Medical - Pharmaceuticals Stocks
The companies in this industry manufacture and process pharmaceutical products in the treatment of health disorders and illnesses. Demand for pharmaceuticals is driven by the desire to cure illness and disease. The profitability of individual companies depends on their ability to discover and market new drugs.
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B
Industry Rank
This industry ranks #2 out of 123 stock categories.
C
Average POWR Rating
The average market cap-weighted POWR Rating for stocks in this industry is C (Neutral).
| Rk | Symbol | Name | Last | Open | High | Low | 52WK Hi | 52WK Lo | Day Chg | YTD Chg | 12M Chg | Mkt Cap | 50D MA | ± 50D | 200D MA | ± 200D | POWR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | RARX | Ra Pharmaceuticals, Inc. | 48.01 | 47.96 | 48.02 | 47.96 | 48.02 | 19.64 | 0.67 (1.42%) | 2.30% | 114.33% | 2.27B | 46.41 | 3.46% | 39.34 | 22.04% | A Strong Buy |
| 2 | KALA | Kala Pharmaceuticals, Inc. | 8.79 | 7.43 | 8.82 | 7.43 | 8.92 | 3.24 | 1.30 (17.36%) | 138.21% | 6.29% | 339.06M | 6.73 | 30.55% | 5.07 | 73.46% | A Strong Buy |
| 3 | NVO | Novo Nordisk A/S | 60.20 | 60.09 | 60.77 | 59.54 | 64.82 | 46.47 | 0.02 (0.03%) | 5.05% | 15.08% | 142.55B | 59.16 | 1.76% | 54.32 | 10.82% | B Buy |
| 4 | LLY | Eli Lilly and Company | 138.72 | 136.96 | 142.02 | 134.52 | 147.87 | 101.36 | 0.28 (0.20%) | 6.09% | 6.91% | 132.76B | 137.36 | 0.99% | 120.04 | 15.56% | B Buy |
| 5 | AZN | Astrazeneca PLC | 44.66 | 44.01 | 45.11 | 43.86 | 51.55 | 36.15 | 0.13 (0.29%) | -8.64% | 10.46% | 117.20B | 45.81 | -2.51% | 44.72 | -0.14% | B Buy |
| 6 | AGN | Allergan plc Ordinary Shares | 177.10 | 175.86 | 179.02 | 175.15 | 202.21 | 114.27 | 0.79 (0.45%) | -7.02% | 20.96% | 58.27B | 187.14 | -5.36% | 174.29 | 1.61% | B Buy |
| 7 | RDY | Dr. Reddy's Laboratories Ltd | 40.33 | 41.40 | 41.64 | 40.28 | 46.19 | 33.33 | 0.07 (0.17%) | -0.62% | -0.42% | 6.68B | 41.83 | -3.59% | 39.27 | 2.69% | B Buy |
| 8 | SNDX | Syndax Pharmaceuticals, Inc. | 10.97 | 10.74 | 11.37 | 10.46 | 12.27 | 4.82 | 0.35 (3.30%) | 24.94% | 108.95% | 331.74M | 9.54 | 14.97% | 8.61 | 27.35% | B Buy |
| 9 | AVDL | Avadel Pharmaceuticals plc each representing one Ordinary Share | 7.94 | 8.66 | 9.39 | 7.85 | 10.75 | 1.03 | -0.78 (-8.94%) | 5.17% | 451.39% | 297.35M | 7.82 | 1.57% | 5.01 | 58.38% | B Buy |
| 10 | SMMT | Summit Therapeutics plc | 2.37 | 2.37 | 2.40 | 2.30 | 3.10 | 1.13 | 0.00 (0.00%) | 48.13% | 29.51% | 76.08M | 1.78 | 33.48% | 1.55 | 52.88% | B Buy |
| 11 | JNJ | Johnson & Johnson | 131.13 | 134.99 | 135.71 | 130.05 | 154.50 | 109.16 | -1.88 (-1.41%) | -9.53% | -6.19% | 345.70B | 140.46 | -6.64% | 135.10 | -2.94% | C Neutral |
| 12 | MRK | Merck & Company, Inc. (new) | 76.94 | 76.25 | 77.60 | 75.52 | 92.64 | 65.25 | -0.01 (-0.01%) | -14.71% | -7.49% | 195.14B | 79.93 | -3.74% | 83.00 | -7.30% | C Neutral |
| 13 | NVS | Novartis AG | 82.45 | 81.29 | 83.21 | 80.60 | 99.84 | 69.18 | 0.55 (0.67%) | -10.87% | -2.50% | 188.96B | 86.64 | -4.84% | 87.81 | -6.10% | C Neutral |
| 14 | ABT | Abbott Laboratories | 78.91 | 81.43 | 81.49 | 78.56 | 92.45 | 61.61 | -0.43 (-0.54%) | -8.77% | -1.29% | 139.15B | 82.69 | -4.58% | 83.63 | -5.64% | C Neutral |
| 15 | BMY | Bristol-Myers Squibb Company | 55.74 | 54.30 | 56.23 | 54.24 | 68.34 | 42.48 | 1.35 (2.48%) | -12.55% | 16.83% | 125.83B | 60.19 | -7.39% | 54.24 | 2.77% | C Neutral |
| 16 | ABBV | AbbVie Inc. | 76.19 | 75.40 | 77.92 | 74.44 | 97.86 | 62.55 | 0.95 (1.26%) | -12.79% | -5.46% | 112.51B | 84.25 | -9.56% | 77.40 | -1.56% | C Neutral |
| 17 | SNY | Sanofi - ADR | 43.72 | 44.14 | 44.50 | 43.10 | 51.84 | 37.62 | -0.97 (-2.17%) | -12.91% | -1.26% | 109.48B | 47.07 | -7.11% | 45.80 | -4.54% | C Neutral |
| 18 | GSK | GlaxoSmithKline PLC | 37.89 | 37.45 | 38.42 | 37.34 | 48.25 | 31.43 | 0.29 (0.77%) | -18.25% | -9.33% | 94.55B | 41.40 | -8.48% | 41.83 | -9.41% | C Neutral |
| 19 | ZTS | Zoetis Inc. | 117.69 | 115.68 | 120.25 | 113.90 | 146.26 | 90.14 | 1.01 (0.87%) | -10.95% | 16.91% | 55.89B | 130.65 | -9.92% | 124.64 | -5.58% | C Neutral |
| 20 | GRFS | Grifols, S.A. | 20.14 | 19.73 | 20.34 | 19.37 | 25.73 | 13.40 | -0.46 (-2.23%) | -13.53% | 0.15% | 13.85B | 22.01 | -8.50% | 21.69 | -7.14% | C Neutral |
| 21 | NBIX | Neurocrine Biosciences, Inc. | 86.55 | 91.27 | 92.39 | 86.02 | 119.65 | 71.85 | -5.04 (-5.50%) | -19.48% | -1.76% | 7.99B | 95.24 | -9.12% | 97.94 | -11.63% | C Neutral |
| 22 | CTLT | Catalent, Inc. | 51.95 | 50.20 | 52.48 | 50.01 | 68.78 | 31.04 | 1.50 (2.97%) | -7.73% | 27.99% | 7.61B | 53.72 | -3.30% | 53.05 | -2.07% | C Neutral |
| 23 | ACAD | ACADIA Pharmaceuticals Inc. | 42.25 | 43.52 | 44.49 | 41.02 | 53.70 | 21.56 | 0.93 (2.25%) | -1.24% | 57.36% | 6.56B | 40.67 | 3.87% | 37.70 | 12.08% | C Neutral |
| 24 | PRGO | Perrigo Company plc Ordinary Shares | 48.09 | 48.10 | 49.42 | 47.62 | 63.86 | 40.17 | -0.72 (-1.48%) | -6.56% | -0.15% | 6.55B | 53.72 | -10.48% | 51.56 | -6.73% | C Neutral |
| 25 | HZNP | Horizon Therapeutics Public Limited Company - Ordinary Shares | 29.62 | 29.30 | 30.09 | 28.90 | 39.10 | 22.69 | 0.27 (0.92%) | -18.18% | 12.07% | 5.63B | 33.05 | -10.37% | 29.73 | -0.37% | C Neutral |
| 26 | UTHR | United Therapeutics Corporation | 94.82 | 96.42 | 96.68 | 92.16 | 121.11 | 74.31 | -2.25 (-2.32%) | 7.65% | -19.21% | 4.16B | 96.54 | -1.79% | 87.27 | 8.65% | C Neutral |
| 27 | MNTA | Momenta Pharmaceuticals, Inc. | 27.20 | 28.05 | 29.28 | 26.55 | 34.83 | 9.51 | -1.54 (-5.36%) | 37.86% | 87.20% | 3.19B | 29.13 | -6.62% | 18.23 | 49.22% | C Neutral |
| 28 | PRNB | Principia Biopharma Inc. | 59.38 | 59.77 | 63.00 | 55.69 | 75.65 | 25.35 | -0.54 (-0.90%) | 8.40% | 74.65% | 1.96B | 59.12 | 0.44% | 43.50 | 36.51% | C Neutral |
| 29 | EIDX | Eidos Therapeutics, Inc. | 48.99 | 49.00 | 50.47 | 46.33 | 66.56 | 22.06 | 0.10 (0.20%) | -14.64% | 108.91% | 1.89B | 49.72 | -1.47% | 45.59 | 7.47% | C Neutral |
| 30 | AUPH | Aurinia Pharmaceuticals Inc | 14.51 | 14.50 | 14.79 | 14.12 | 21.93 | 3.52 | -0.19 (-1.29%) | -28.38% | 123.23% | 1.63B | 16.97 | -14.51% | 10.67 | 36.04% | C Neutral |
| 31 | IRWD | Ironwood Pharmaceuticals, Inc. - | 10.09 | 10.29 | 10.46 | 9.94 | 14.10 | 7.91 | -0.24 (-2.32%) | -24.19% | -25.42% | 1.60B | 11.45 | -11.88% | 10.83 | -6.79% | C Neutral |
| 32 | ARVN | Arvinas, Inc. | 40.30 | 41.27 | 42.61 | 38.06 | 54.95 | 14.74 | -0.79 (-1.92%) | -1.92% | 173.04% | 1.57B | 46.92 | -14.11% | 32.84 | 22.72% | C Neutral |
| 33 | KPTI | Karyopharm Therapeutics Inc. | 19.21 | 19.84 | 20.23 | 18.30 | 29.61 | 4.26 | -0.81 (-4.05%) | 0.21% | 228.94% | 1.26B | 18.41 | 4.33% | 13.53 | 42.03% | C Neutral |
| 34 | ZEAL | Zealand Pharma A/S | 34.50 | 33.57 | 35.00 | 33.51 | 44.60 | 18.07 | 3.42 (11.00%) | 3.92% | 102.70% | 1.24B | 34.96 | -1.32% | 28.60 | 20.63% | C Neutral |
| 35 | YMAB | Y-mAbs Therapeutics, Inc. | 26.10 | 24.37 | 26.30 | 22.71 | 36.29 | 14.16 | 2.97 (12.84%) | -16.48% | -0.42% | 1.04B | 28.53 | -8.52% | 27.75 | -5.94% | C Neutral |
| 36 | KNSA | Kiniksa Pharmaceuticals, Ltd. - | 15.48 | 16.74 | 17.46 | 14.52 | 21.50 | 5.01 | 3.26 (26.68%) | 39.96% | -14.29% | 859.84M | 16.03 | -3.41% | 11.85 | 30.62% | C Neutral |
| 37 | EGRX | Eagle Pharmaceuticals, Inc. | 46.00 | 45.18 | 46.40 | 43.45 | 64.94 | 33.80 | 0.69 (1.52%) | -23.44% | -8.89% | 629.23M | 48.12 | -4.41% | 55.34 | -16.88% | C Neutral |
| 38 | MTEM | Molecular Templates, Inc. | 13.29 | 13.98 | 14.39 | 12.69 | 19.12 | 4.51 | -0.79 (-5.61%) | -4.97% | 128.74% | 606.66M | 14.78 | -10.06% | 9.98 | 33.19% | C Neutral |
| 39 | ACIU | AC Immune SA | 6.91 | 7.30 | 7.30 | 6.52 | 10.14 | 4.07 | -0.39 (-5.34%) | -18.90% | 36.83% | 466.85M | 7.44 | -7.18% | 6.55 | 5.55% | C Neutral |
| 40 | TRIL | Trillium Therapeutics Inc. | 4.04 | 3.91 | 4.32 | 3.90 | 7.97 | 0.24 | 0.11 (2.80%) | 292.23% | 512.12% | 331.92M | 4.18 | -3.25% | 1.42 | 184.60% | C Neutral |
| 41 | KMDA | Kamada Ltd. - Ordinary Shares | 5.83 | 5.93 | 6.14 | 5.75 | 8.00 | 4.40 | 0.07 (1.22%) | -14.64% | 1.75% | 259.55M | 5.99 | -2.63% | 5.87 | -0.76% | C Neutral |
| 42 | STRO | Sutro Biopharma, Inc. | 10.20 | 10.30 | 10.30 | 9.75 | 12.75 | 6.00 | -0.05 (-0.49%) | -7.27% | -10.45% | 235.61M | 10.18 | 0.20% | 10.37 | -1.62% | C Neutral |
| 43 | VERU | Veru Inc. | 3.27 | 3.27 | 3.29 | 3.16 | 4.74 | 1.18 | 0.00 (0.00%) | -2.39% | 123.97% | 213.18M | 3.73 | -12.27% | 2.65 | 23.42% | C Neutral |
| 44 | ARCT | Arcturus Therapeutics Holdings Inc. | 13.59 | 13.47 | 14.31 | 13.00 | 19.00 | 5.70 | 0.34 (2.57%) | 25.02% | 98.98% | 205.73M | 13.20 | 2.97% | 11.21 | 21.24% | C Neutral |
| 45 | SCPH | scPharmaceuticals Inc. | 7.40 | 7.26 | 7.74 | 7.26 | 10.95 | 2.44 | 0.01 (0.14%) | 30.74% | 146.67% | 155.27M | 7.61 | -2.77% | 5.85 | 26.50% | C Neutral |
| 46 | ATXI | Avenue Therapeutics, Inc. | 8.94 | 8.52 | 9.13 | 8.52 | 11.47 | 4.13 | 0.53 (6.30%) | -6.88% | 88.21% | 148.95M | 8.92 | 0.23% | 6.98 | 28.01% | C Neutral |
| 47 | FENC | Fennec Pharmaceuticals Inc. | 5.94 | 5.83 | 5.96 | 5.65 | 8.40 | 3.26 | 0.18 (3.13%) | -8.47% | 22.47% | 118.18M | 6.51 | -8.77% | 5.35 | 11.02% | C Neutral |
| 48 | EPIX | ESSA Pharma Inc. | 4.00 | 4.00 | 4.21 | 3.85 | 6.14 | 1.41 | 0.00 (0.00%) | -27.27% | 17.36% | 83.05M | 4.87 | -17.89% | 3.96 | 1.13% | C Neutral |
| 49 | NTGN | Neon Therapeutics, Inc. | 2.64 | 2.50 | 2.90 | 2.30 | 7.51 | 0.88 | 0.19 (7.76%) | 123.73% | -59.13% | 76.19M | 1.73 | 52.72% | 2.23 | 18.47% | C Neutral |
| 50 | VBLT | Vascular Biogenics Ltd. - Ordinary Shares | 1.35 | 1.29 | 1.35 | 1.19 | 1.71 | 0.90 | 0.00 (0.00%) | 12.50% | -11.18% | 48.44M | 1.35 | 0.22% | 1.28 | 5.77% | C Neutral |
| 51 | PFE | Pfizer, Inc. | 32.64 | 32.40 | 33.00 | 32.23 | 44.56 | 27.88 | -0.03 (-0.09%) | -15.84% | -23.15% | 181.07B | 34.99 | -6.72% | 37.03 | -11.86% | D Sell |
| 52 | TEVA | Teva Pharmaceutical Industries Limited American Depositary Shares | 8.98 | 8.98 | 9.43 | 8.85 | 15.86 | 6.07 | 0.47 (5.52%) | -8.37% | -42.73% | 9.81B | 10.42 | -13.79% | 8.91 | 0.76% | D Sell |
| 53 | ELAN | Elanco Animal Health Incorporated | 22.39 | 22.64 | 23.15 | 22.12 | 35.46 | 15.17 | -0.20 (-0.89%) | -23.97% | -30.18% | 8.92B | 26.95 | -16.93% | 28.46 | -21.32% | D Sell |
| 54 | BGNE | BeiGene, Ltd. | 123.11 | 124.31 | 126.65 | 122.52 | 210.35 | 113.01 | -2.28 (-1.82%) | -25.73% | -6.73% | 8.02B | 154.27 | -20.20% | 150.19 | -18.03% | D Sell |
| 55 | NVCR | NovoCure Limited - Ordinary Shares | 67.34 | 69.50 | 69.68 | 65.57 | 98.84 | 41.51 | -2.70 (-3.85%) | -20.09% | 39.80% | 6.71B | 78.24 | -13.93% | 78.90 | -14.65% | D Sell |
| 56 | IONS | Ionis Pharmaceuticals, Inc. | 47.28 | 48.00 | 48.63 | 46.88 | 86.58 | 39.32 | -0.93 (-1.93%) | -21.73% | -41.75% | 6.58B | 54.29 | -12.91% | 60.43 | -21.75% | D Sell |
| 57 | CGC | Canopy Growth Corporation | 14.42 | 13.99 | 15.47 | 13.99 | 52.74 | 9.00 | -0.04 (-0.28%) | -31.63% | -66.75% | 5.04B | 18.04 | -20.06% | 24.02 | -39.96% | D Sell |
| 58 | RETA | Reata Pharmaceuticals, Inc. - | 144.34 | 143.91 | 152.52 | 139.51 | 257.96 | 70.00 | -17.54 (-10.84%) | -29.39% | 68.88% | 4.80B | 189.39 | -23.79% | 149.73 | -3.60% | D Sell |
| 59 | MOR | MorphoSys AG | 24.57 | 24.87 | 25.06 | 24.37 | 37.96 | 18.21 | -0.95 (-3.72%) | -31.12% | 8.14% | 3.23B | 28.13 | -12.67% | 29.10 | -15.56% | D Sell |
| 60 | GWPH | GW Pharmaceuticals Plc | 87.57 | 86.00 | 88.80 | 85.51 | 196.00 | 67.98 | 2.39 (2.81%) | -16.25% | -48.05% | 2.71B | 104.88 | -16.51% | 125.92 | -30.45% | D Sell |
| 61 | ALLO | Allogene Therapeutics, Inc. | 19.44 | 19.96 | 20.10 | 18.77 | 33.80 | 17.43 | -0.64 (-3.19%) | -25.17% | -32.76% | 2.43B | 23.25 | -16.40% | 26.66 | -27.09% | D Sell |
| 62 | TARO | Taro Pharmaceutical Industries Ltd. Ordinary Shares | 61.20 | 62.50 | 62.64 | 60.39 | 109.42 | 56.07 | -1.29 (-2.06%) | -30.40% | -43.38% | 2.34B | 71.10 | -13.92% | 80.24 | -23.73% | D Sell |
| 63 | MYOK | MyoKardia, Inc. | 46.88 | 50.94 | 51.87 | 45.56 | 78.28 | 43.50 | -4.52 (-8.79%) | -35.68% | -9.83% | 2.18B | 62.06 | -24.45% | 58.67 | -20.10% | D Sell |
| 64 | AXSM | Axsome Therapeutics, Inc. | 58.83 | 56.67 | 60.72 | 56.67 | 109.94 | 12.76 | 1.25 (2.17%) | -43.08% | 313.42% | 2.18B | 79.01 | -25.54% | 47.62 | 23.54% | D Sell |
| 65 | APLS | Apellis Pharmaceuticals, Inc. | 26.79 | 28.96 | 29.66 | 26.39 | 45.04 | 16.85 | -1.89 (-6.59%) | -12.51% | 37.38% | 2.02B | 35.00 | -23.45% | 29.85 | -10.26% | D Sell |
| 66 | DNLI | Denali Therapeutics Inc. | 17.51 | 19.63 | 19.65 | 17.17 | 30.41 | 12.39 | -2.19 (-11.12%) | 0.52% | -24.59% | 1.85B | 21.25 | -17.58% | 18.91 | -7.40% | D Sell |
| 67 | PCRX | Pacira BioSciences, Inc. | 33.53 | 33.48 | 33.99 | 32.93 | 51.35 | 27.46 | -0.18 (-0.53%) | -25.98% | -11.90% | 1.41B | 41.08 | -18.38% | 41.42 | -19.04% | D Sell |
| 68 | CNST | Constellation Pharmaceuticals, Inc. | 31.43 | 30.95 | 31.95 | 29.13 | 59.49 | 6.01 | 0.62 (2.01%) | -33.28% | 131.96% | 1.31B | 33.43 | -5.98% | 23.19 | 35.54% | D Sell |
| 69 | ZGNX | Zogenix, Inc. | 24.73 | 25.62 | 26.09 | 23.92 | 57.22 | 16.65 | -0.85 (-3.32%) | -52.56% | -55.04% | 1.12B | 32.34 | -23.54% | 42.77 | -42.18% | D Sell |
| 70 | TCDA | Tricida, Inc. | 22.00 | 23.33 | 23.52 | 21.84 | 44.30 | 18.02 | -1.35 (-5.78%) | -41.71% | -43.03% | 1.10B | 31.16 | -29.39% | 34.42 | -36.08% | D Sell |
| 71 | SUPN | Supernus Pharmaceuticals, Inc. | 17.99 | 17.24 | 18.35 | 16.93 | 39.15 | 13.12 | 0.83 (4.84%) | -24.16% | -48.66% | 945.09M | 20.32 | -11.47% | 25.33 | -28.98% | D Sell |
| 72 | AIMT | Aimmune Therapeutics, Inc. | 14.42 | 14.59 | 15.30 | 14.02 | 37.00 | 10.09 | -0.13 (-0.89%) | -56.92% | -35.48% | 903.69M | 23.52 | -38.68% | 24.40 | -40.91% | D Sell |
| 73 | ODT | Odonate Therapeutics, Inc. | 27.61 | 28.28 | 28.88 | 25.34 | 43.75 | 16.50 | -0.68 (-2.40%) | -14.92% | 24.88% | 885.26M | 29.15 | -5.30% | 31.14 | -11.34% | D Sell |
| 74 | ENDP | Endo International plc - Ordinary Shares | 3.70 | 3.71 | 3.97 | 3.60 | 8.55 | 1.97 | 0.04 (1.09%) | -21.11% | -53.92% | 839.29M | 5.08 | -27.17% | 4.22 | -12.41% | D Sell |
| 75 | APHA | Aphria Inc. Common Shares | 3.06 | 3.02 | 3.25 | 2.96 | 10.17 | 1.95 | -0.02 (-0.65%) | -41.38% | -67.17% | 817.67M | 3.75 | -18.35% | 5.19 | -41.01% | D Sell |
| 76 | APLT | Applied Therapeutics, Inc. | 32.69 | 33.24 | 35.92 | 30.70 | 57.39 | 7.95 | -1.30 (-3.82%) | 19.83% | 247.77% | 718.17M | 40.91 | -20.09% | 21.47 | 52.28% | D Sell |
| 77 | TLRY | Tilray, Inc. - Class 2 | 6.88 | 6.13 | 7.84 | 6.00 | 65.21 | 2.43 | 0.27 (4.08%) | -59.84% | -89.50% | 715.91M | 13.08 | -47.40% | 24.92 | -72.39% | D Sell |
| 78 | FIXX | Homology Medicines, Inc. | 15.54 | 16.14 | 16.43 | 15.10 | 31.50 | 11.05 | -0.60 (-3.72%) | -24.93% | -43.96% | 702.45M | 16.77 | -7.31% | 17.37 | -10.52% | D Sell |
| 79 | AMPH | Amphastar Pharmaceuticals, Inc. | 14.84 | 15.06 | 15.32 | 14.46 | 23.06 | 12.32 | -0.28 (-1.85%) | -23.07% | -27.36% | 686.17M | 16.99 | -12.66% | 19.23 | -22.82% | D Sell |
| 80 | RTRX | Retrophin, Inc. | 14.59 | 14.23 | 14.80 | 13.97 | 23.26 | 8.98 | 0.34 (2.39%) | 2.75% | -35.53% | 629.06M | 15.00 | -2.76% | 15.05 | -3.03% | D Sell |
| 81 | COLL | Collegium Pharmaceutical, Inc. | 16.33 | 16.73 | 17.10 | 15.97 | 25.59 | 10.01 | -0.59 (-3.49%) | -20.65% | 7.86% | 559.51M | 20.19 | -19.13% | 16.01 | 2.03% | D Sell |
| 82 | MGTX | MeiraGTx Holdings plc - Ordinary Shares | 13.44 | 12.34 | 13.45 | 11.77 | 30.23 | 8.82 | 0.98 (7.87%) | -32.87% | -22.00% | 494.83M | 16.12 | -16.61% | 19.29 | -30.33% | D Sell |
| 83 | ASMB | Assembly Biosciences, Inc. | 14.83 | 15.31 | 15.67 | 14.01 | 25.07 | 8.13 | -0.46 (-3.01%) | -27.52% | -24.68% | 483.83M | 17.49 | -15.20% | 15.17 | -2.25% | D Sell |
| 84 | MESO | Mesoblast Limited | 4.38 | 4.49 | 4.49 | 4.21 | 10.88 | 3.12 | 0.04 (0.92%) | -40.57% | -16.57% | 470.52M | 7.58 | -42.19% | 6.41 | -31.70% | D Sell |
| 85 | BTAI | BioXcel Therapeutics, Inc. | 22.35 | 24.23 | 25.14 | 21.21 | 43.63 | 3.76 | -1.96 (-8.06%) | 52.98% | 125.99% | 451.07M | 24.20 | -7.66% | 12.67 | 76.36% | D Sell |
| 86 | CPRX | Catalyst Pharmaceuticals, Inc. | 3.85 | 3.95 | 4.05 | 3.68 | 7.67 | 2.23 | -0.03 (-0.77%) | 2.67% | -24.51% | 398.12M | 4.08 | -5.53% | 4.66 | -17.37% | D Sell |
| 87 | CUE | Cue Biopharma, Inc. | 14.19 | 13.74 | 14.36 | 13.01 | 22.82 | 6.54 | 0.47 (3.43%) | -10.61% | 83.57% | 377.11M | 16.35 | -13.20% | 11.31 | 25.46% | D Sell |
| 88 | CTMX | CytomX Therapeutics, Inc. | 7.67 | 7.09 | 7.84 | 6.75 | 12.63 | 3.60 | 0.97 (14.48%) | -7.70% | -28.65% | 349.50M | 6.76 | 13.42% | 8.02 | -4.32% | D Sell |
| 89 | VKTX | Viking Therapeutics, Inc. | 4.68 | 4.73 | 4.80 | 4.49 | 11.03 | 3.26 | -0.06 (-1.27%) | -41.65% | -52.92% | 339.59M | 5.81 | -19.44% | 7.02 | -33.35% | D Sell |
| 90 | BYSI | BeyondSpring, Inc. - Ordinary Shares | 12.81 | 12.56 | 13.80 | 12.13 | 24.80 | 9.38 | 0.04 (0.31%) | -17.35% | -20.01% | 332.60M | 15.00 | -14.59% | 16.33 | -21.57% | D Sell |
| 91 | DRRX | DURECT Corporation | 1.55 | 1.46 | 1.59 | 1.46 | 3.95 | 0.50 | 0.05 (3.33%) | -59.21% | 147.64% | 303.52M | 1.76 | -11.94% | 1.71 | -9.35% | D Sell |
| 92 | CDMO | Avid Bioservices, Inc. | 5.11 | 5.16 | 5.69 | 4.77 | 8.38 | 3.02 | 0.19 (3.86%) | -33.38% | 20.24% | 288.62M | 5.87 | -12.92% | 5.93 | -13.86% | D Sell |
| 93 | VRCA | Verrica Pharmaceuticals Inc. | 10.93 | 11.32 | 11.35 | 10.00 | 18.67 | 6.79 | -0.49 (-4.29%) | -31.21% | 1.11% | 281.84M | 12.66 | -13.70% | 12.84 | -14.91% | D Sell |
| 94 | UROV | Urovant Sciences Ltd. | 9.22 | 9.09 | 10.21 | 9.01 | 15.98 | 6.45 | 0.20 (2.22%) | -40.55% | -8.26% | 281.39M | 11.60 | -20.52% | 10.37 | -11.12% | D Sell |
| 95 | RIGL | Rigel Pharmaceuticals, Inc. | 1.56 | 1.53 | 1.59 | 1.48 | 3.10 | 1.23 | 0.03 (1.96%) | -27.10% | -39.30% | 262.97M | 2.08 | -24.92% | 2.10 | -25.57% | D Sell |
| 96 | SYRS | Syros Pharmaceuticals, Inc. - common stock | 5.93 | 5.40 | 6.11 | 5.39 | 11.93 | 4.26 | 0.52 (9.61%) | -14.18% | -35.12% | 257.35M | 6.50 | -8.72% | 7.43 | -20.17% | D Sell |
| 97 | ALBO | Albireo Pharma, Inc. | 16.37 | 16.20 | 16.57 | 14.90 | 38.69 | 11.26 | 0.08 (0.49%) | -35.60% | -49.18% | 244.67M | 21.13 | -22.52% | 23.09 | -29.09% | D Sell |
| 98 | AMAG | AMAG Pharmaceuticals, Inc. | 6.18 | 6.15 | 6.31 | 5.91 | 13.53 | 4.41 | 0.01 (0.16%) | -49.22% | -52.02% | 211.76M | 7.99 | -22.70% | 10.04 | -38.44% | D Sell |
| 99 | PTGX | Protagonist Therapeutics, Inc. | 7.06 | 7.16 | 7.36 | 6.86 | 16.67 | 4.47 | -0.11 (-1.53%) | 0.14% | -43.83% | 192.70M | 7.63 | -7.43% | 10.13 | -30.28% | D Sell |
| 100 | MEIP | MEI Pharma, Inc. | 1.61 | 1.59 | 1.67 | 1.45 | 3.41 | 0.72 | 0.17 (11.81%) | -35.08% | -47.56% | 170.66M | 1.94 | -17.00% | 1.92 | -16.34% | D Sell |
| 101 | MNK | Mallinckrodt plc Ordinary Shares | 1.98 | 2.25 | 2.39 | 1.83 | 23.90 | 1.00 | -0.27 (-12.00%) | -43.27% | -90.89% | 166.73M | 3.81 | -47.99% | 4.26 | -53.49% | D Sell |
| 102 | SPRO | Spero Therapeutics, Inc. | 8.08 | 8.00 | 8.10 | 7.33 | 14.48 | 5.25 | 0.08 (1.00%) | -15.96% | -36.92% | 164.25M | 8.71 | -7.25% | 10.19 | -20.71% | D Sell |
| 103 | NYMX | Nymox Pharmaceutical Corporation | 2.34 | 2.17 | 2.43 | 2.17 | 4.09 | 1.32 | 0.16 (7.34%) | 6.36% | 18.78% | 163.73M | 2.76 | -15.33% | 2.14 | 9.10% | D Sell |
| 104 | TYME | Tyme Technologies, Inc. | 1.10 | 1.03 | 1.11 | 1.01 | 2.04 | 0.86 | 0.04 (3.77%) | -21.43% | -37.50% | 135.12M | 1.26 | -12.66% | 1.26 | -12.74% | D Sell |
| 105 | LQDA | Liquidia Technologies, Inc. | 4.71 | 4.96 | 5.00 | 4.62 | 11.90 | 2.65 | -0.22 (-4.46%) | 10.18% | -58.61% | 133.61M | 4.96 | -5.09% | 5.13 | -8.22% | D Sell |
| 106 | VTVT | vTv Therapeutics Inc. - | 1.91 | 1.91 | 2.07 | 1.86 | 4.23 | 1.23 | 0.02 (1.06%) | 12.35% | 11.70% | 124.65M | 2.50 | -23.65% | 1.75 | 9.02% | D Sell |
| 107 | APM | Aptorum Group Limited - Class A Ordinary Shares | 3.65 | 3.19 | 4.24 | 3.19 | 33.28 | 1.66 | 0.64 (21.26%) | -76.97% | -72.88% | 105.76M | 9.27 | -60.61% | 15.44 | -76.36% | D Sell |
| 108 | RDHL | Redhill Biopharma Ltd. | 4.53 | 4.34 | 4.64 | 4.28 | 8.94 | 3.26 | 0.16 (3.66%) | -25.37% | -45.49% | 99.37M | 4.75 | -4.70% | 6.26 | -27.68% | D Sell |
| 109 | ERYP | Erytech Pharma S.A. | 5.34 | 5.00 | 5.39 | 4.99 | 8.49 | 3.50 | 0.34 (6.80%) | -27.59% | -29.55% | 95.80M | 6.26 | -14.67% | 6.72 | -20.56% | D Sell |
| 110 | APTX | Aptinyx Inc. | 2.16 | 2.37 | 2.38 | 2.07 | 5.25 | 1.60 | -0.16 (-6.90%) | -36.84% | -46.67% | 94.71M | 3.19 | -32.34% | 3.43 | -36.99% | D Sell |
| 111 | ZYNE | Zynerba Pharmaceuticals, Inc. | 3.83 | 3.64 | 3.84 | 3.57 | 16.47 | 2.55 | 0.16 (4.36%) | -36.59% | -29.34% | 90.22M | 4.39 | -12.85% | 7.90 | -51.49% | D Sell |
| 112 | IDYA | IDEAYA Biosciences, Inc. | 4.12 | 4.17 | 4.31 | 3.91 | 16.90 | 2.95 | -0.03 (-0.72%) | -45.07% | -63.18% | 83.82M | 6.52 | -36.83% | 7.43 | -44.56% | D Sell |
| 113 | ADMS | Adamas Pharmaceuticals, Inc. | 2.89 | 2.75 | 2.98 | 2.70 | 7.78 | 1.90 | 0.13 (4.71%) | -23.75% | -59.35% | 80.96M | 4.34 | -33.43% | 5.17 | -44.15% | D Sell |
| 114 | CLSD | Clearside Biomedical, Inc. | 1.70 | 1.77 | 1.84 | 1.56 | 4.13 | 0.56 | -0.06 (-3.41%) | -41.38% | 23.19% | 76.28M | 2.50 | -31.87% | 1.57 | 8.31% | D Sell |
| 115 | SCYX | SCYNEXIS, Inc. | 0.78 | 0.79 | 0.83 | 0.77 | 1.90 | 0.50 | 0.04 (6.10%) | -14.29% | -48.28% | 76.08M | 0.88 | -11.01% | 1.04 | -24.92% | D Sell |
| 116 | ORGS | Orgenesis Inc. | 3.80 | 3.45 | 4.01 | 3.32 | 6.49 | 2.35 | 0.49 (14.80%) | -18.45% | -28.71% | 69.77M | 4.26 | -10.75% | 4.07 | -6.53% | D Sell |
| 117 | ARDS | Aridis Pharmaceuticals Inc. | 5.77 | 5.77 | 5.77 | 5.77 | 12.40 | 3.80 | -0.03 (-0.52%) | 29.66% | -49.39% | 51.42M | 6.41 | -10.01% | 7.08 | -18.55% | D Sell |
| 118 | ACRS | Aclaris Therapeutics, Inc. | 1.04 | 1.00 | 1.17 | 1.00 | 7.15 | 0.70 | 0.02 (1.96%) | -44.97% | -82.64% | 43.19M | 1.22 | -15.00% | 1.62 | -35.66% | D Sell |
| 119 | VVUS | VIVUS, Inc. | 3.60 | 3.94 | 4.55 | 2.73 | 4.75 | 0.80 | 2.65 (278.95%) | 32.35% | -14.29% | 38.34M | 1.96 | 83.57% | 3.05 | 18.17% | D Sell |
| 120 | ITRM | Iterum Therapeutics plc - Ordinary Share | 2.71 | 2.85 | 2.90 | 2.59 | 9.30 | 1.40 | -0.09 (-3.21%) | -39.78% | -65.79% | 37.83M | 2.46 | 10.15% | 4.32 | -37.30% | D Sell |
| 121 | LPCN | Lipocine Inc. | 0.48 | 0.48 | 0.51 | 0.47 | 3.45 | 0.30 | 0.01 (1.10%) | 24.71% | -79.22% | 22.97M | 0.47 | 2.33% | 1.47 | -67.44% | D Sell |
| 122 | NOVN | Novan, Inc. | 0.48 | 0.48 | 0.48 | 0.42 | 3.72 | 0.22 | 0.00 (0.00%) | -84.81% | -50.26% | 21.74M | 0.48 | -0.87% | 1.90 | -74.70% | D Sell |
| 123 | CORV | Correvio Pharma Corp. - Ordinary Shares (Canada) | 0.39 | 0.37 | 0.39 | 0.36 | 3.22 | 0.21 | 0.02 (4.27%) | -4.88% | -87.72% | 21.49M | 0.35 | 10.36% | 1.41 | -72.34% | D Sell |
| 124 | TTPH | Tetraphase Pharmaceuticals, Inc. | 1.28 | 1.62 | 1.75 | 1.25 | 27.40 | 0.56 | -0.36 (-21.95%) | -54.45% | -95.22% | 9.29M | 1.86 | -31.24% | 4.38 | -70.75% | D Sell |
| 125 | TRPX | Therapix Biosciences Ltd. | 0.43 | 0.45 | 0.46 | 0.42 | 4.69 | 0.29 | 0.00 (0.05%) | -61.47% | -86.25% | 1.51M | 0.49 | -11.37% | 1.70 | -74.70% | D Sell |
| 126 | MYL | Mylan N.V. | 14.91 | 15.07 | 15.80 | 14.84 | 28.88 | 12.75 | -0.16 (-1.06%) | -25.82% | -47.39% | 7.70B | 18.68 | -20.20% | 19.08 | -21.86% | F Strong Sell |
| 127 | BHC | Bausch Health Companies Inc. | 15.50 | 15.33 | 16.27 | 15.10 | 31.97 | 11.15 | 0.25 (1.64%) | -48.20% | -37.25% | 5.46B | 22.97 | -32.51% | 24.31 | -36.23% | F Strong Sell |
| 128 | ALKS | Alkermes plc - Ordinary Shares | 14.42 | 14.39 | 14.78 | 14.10 | 37.75 | 11.98 | 0.02 (0.14%) | -29.31% | -60.48% | 2.28B | 17.47 | -17.47% | 19.96 | -27.77% | F Strong Sell |
| 129 | AMRN | Amarin Corporation plc, each representing one Ordinary Share | 4.00 | 4.19 | 4.36 | 3.95 | 26.12 | 3.95 | -9.58 (-70.54%) | -81.34% | -80.73% | 1.43B | 15.79 | -74.66% | 17.75 | -77.47% | F Strong Sell |
| 130 | ACB | Aurora Cannabis Inc. Common Shares | 0.91 | 0.92 | 0.98 | 0.87 | 9.37 | 0.60 | 0.02 (2.07%) | -57.87% | -90.00% | 1.06B | 1.39 | -34.50% | 3.81 | -76.11% | F Strong Sell |
| 131 | AMRX | Amneal Pharmaceuticals, Inc. | 3.48 | 3.11 | 3.57 | 3.11 | 14.65 | 2.27 | 0.41 (13.36%) | -27.80% | -75.44% | 1.04B | 4.10 | -15.06% | 3.89 | -10.42% | F Strong Sell |
| 132 | MDGL | Madrigal Pharmaceuticals, Inc. | 66.76 | 69.08 | 69.25 | 62.80 | 145.16 | 60.86 | -3.35 (-4.78%) | -26.73% | -46.70% | 1.03B | 82.34 | -18.92% | 92.00 | -27.43% | F Strong Sell |
| 133 | MYOV | Myovant Sciences Ltd. Common Shares | 7.55 | 8.55 | 8.57 | 7.40 | 26.02 | 4.14 | -0.22 (-2.83%) | -51.35% | -68.37% | 677.90M | 10.49 | -28.02% | 9.54 | -20.83% | F Strong Sell |
| 134 | RYTM | Rhythm Pharmaceuticals, Inc. | 15.22 | 14.51 | 15.36 | 14.18 | 29.13 | 12.99 | 0.72 (4.97%) | -33.71% | -44.47% | 670.58M | 17.08 | -10.87% | 20.63 | -26.22% | F Strong Sell |
| 135 | ATNX | Athenex, Inc. | 7.74 | 8.20 | 8.20 | 7.41 | 21.11 | 5.63 | -0.39 (-4.80%) | -49.31% | -36.82% | 631.79M | 11.89 | -34.90% | 14.27 | -45.77% | F Strong Sell |
| 136 | AERI | Aerie Pharmaceuticals, Inc. | 13.50 | 13.55 | 13.98 | 13.24 | 49.16 | 10.80 | 0.01 (0.07%) | -44.15% | -71.58% | 626.78M | 17.66 | -23.56% | 21.39 | -36.89% | F Strong Sell |
| 137 | RDUS | Radius Health, Inc. | 13.00 | 13.22 | 13.68 | 12.65 | 29.97 | 10.32 | -0.11 (-0.84%) | -35.52% | -34.80% | 600.83M | 17.39 | -25.23% | 22.33 | -41.77% | F Strong Sell |
| 138 | NBRV | Nabriva Therapeutics plc - Ordinary Shares | 0.58 | 0.61 | 0.62 | 0.56 | 3.19 | 0.50 | -0.02 (-3.85%) | -56.06% | -76.43% | 544.08M | 1.20 | -51.65% | 1.80 | -67.73% | F Strong Sell |
| 139 | CLLS | Cellectis S.A. | 9.20 | 9.21 | 9.49 | 9.02 | 20.84 | 7.32 | 0.15 (1.66%) | -46.26% | -49.84% | 390.54M | 14.24 | -35.38% | 13.95 | -34.05% | F Strong Sell |
| 140 | REPL | Replimune Group, Inc. | 9.97 | 10.44 | 10.44 | 9.41 | 19.66 | 8.58 | -0.50 (-4.78%) | -30.52% | -34.49% | 365.36M | 14.43 | -30.89% | 13.83 | -27.93% | F Strong Sell |
| 141 | CRNX | Crinetics Pharmaceuticals, Inc. | 14.70 | 15.04 | 15.04 | 13.77 | 28.81 | 10.63 | -0.40 (-2.65%) | -41.41% | -35.41% | 361.13M | 19.35 | -24.04% | 19.86 | -25.99% | F Strong Sell |
| 142 | VYGR | Voyager Therapeutics, Inc. | 9.15 | 8.72 | 9.41 | 8.72 | 28.79 | 6.26 | 0.40 (4.57%) | -34.41% | -52.19% | 339.95M | 10.91 | -16.13% | 16.26 | -43.74% | F Strong Sell |
| 143 | WVE | Wave Life Sciences Ltd. - Ordinary Shares | 9.37 | 9.17 | 9.64 | 8.97 | 43.00 | 6.61 | 0.17 (1.85%) | 16.91% | -75.88% | 323.66M | 8.62 | 8.71% | 19.15 | -51.06% | F Strong Sell |
| 144 | FLXN | Flexion Therapeutics, Inc. | 7.87 | 8.18 | 8.59 | 7.72 | 22.98 | 5.01 | -0.35 (-4.26%) | -61.98% | -36.94% | 303.40M | 14.04 | -43.94% | 14.44 | -45.50% | F Strong Sell |
| 145 | TXMD | TherapeuticsMD, Inc. | 1.06 | 1.03 | 1.08 | 1.02 | 5.04 | 0.90 | -0.01 (-0.93%) | -56.20% | -78.23% | 287.82M | 1.89 | -43.96% | 2.57 | -58.69% | F Strong Sell |
| 146 | LCI | Lannett Co Inc | 6.95 | 7.53 | 7.70 | 6.86 | 15.52 | 5.16 | -0.58 (-7.70%) | -21.20% | -11.69% | 280.39M | 8.32 | -16.46% | 8.86 | -21.59% | F Strong Sell |
| 147 | MGTA | Magenta Therapeutics, Inc. | 6.28 | 7.12 | 7.12 | 6.22 | 18.40 | 5.76 | -0.85 (-11.92%) | -58.58% | -61.87% | 246.97M | 10.88 | -42.27% | 11.86 | -47.05% | F Strong Sell |
| 148 | OPTN | OptiNose, Inc. | 4.49 | 4.27 | 4.74 | 4.20 | 11.66 | 3.28 | 0.20 (4.66%) | -51.30% | -56.41% | 206.12M | 6.33 | -29.01% | 7.33 | -38.77% | F Strong Sell |
| 149 | RFL | Rafael Holdings, Inc. Class B | 12.81 | 11.08 | 13.47 | 10.86 | 30.86 | 9.40 | 1.48 (13.06%) | -28.20% | 1.26% | 202.63M | 17.53 | -26.94% | 19.29 | -33.60% | F Strong Sell |
| 150 | ABEO | Abeona Therapeutics Inc. | 2.10 | 2.03 | 2.17 | 1.95 | 8.41 | 1.35 | 0.06 (2.94%) | -35.78% | -71.47% | 175.61M | 2.68 | -21.50% | 2.93 | -28.29% | F Strong Sell |
| 151 | OSMT | Osmotica Pharmaceuticals plc - Ordinary Shares | 3.18 | 3.41 | 3.55 | 3.16 | 7.97 | 2.20 | -0.24 (-7.02%) | -54.51% | -11.67% | 163.84M | 5.27 | -39.66% | 4.61 | -31.03% | F Strong Sell |
| 152 | CHMA | Chiasma, Inc. | 3.65 | 3.57 | 3.68 | 3.51 | 9.25 | 2.88 | 0.06 (1.67%) | -26.41% | -29.81% | 154.23M | 4.33 | -15.78% | 5.24 | -30.37% | F Strong Sell |
| 153 | SLGL | Sol-Gel Technologies Ltd. | 7.06 | 7.00 | 7.27 | 6.96 | 21.00 | 5.00 | 0.11 (1.58%) | -58.83% | 4.28% | 143.95M | 10.22 | -30.95% | 9.54 | -25.99% | F Strong Sell |
| 154 | RMTI | Rockwell Medical, Inc. | 2.05 | 1.88 | 2.06 | 1.86 | 6.01 | 1.31 | 0.05 (2.50%) | -15.98% | -63.97% | 141.55M | 2.63 | -22.11% | 2.59 | -20.75% | F Strong Sell |
| 155 | EOLS | Evolus, Inc. | 4.15 | 4.05 | 4.71 | 3.99 | 29.40 | 3.12 | 0.11 (2.72%) | -65.90% | -81.61% | 139.97M | 7.79 | -46.75% | 13.08 | -68.27% | F Strong Sell |
| 156 | TLC | Taiwan Liposome Company, Ltd. - ADRs | 3.70 | 3.52 | 3.70 | 3.52 | 8.54 | 2.48 | 0.00 (0.00%) | -31.23% | -36.59% | 137.26M | 4.71 | -21.52% | 5.13 | -27.88% | F Strong Sell |
| 157 | KALV | KalVista Pharmaceuticals, Inc. | 7.65 | 7.54 | 7.75 | 7.40 | 32.15 | 5.61 | 0.10 (1.32%) | -57.05% | -73.27% | 136.52M | 12.70 | -39.78% | 14.58 | -47.54% | F Strong Sell |
| 158 | AGRX | Agile Therapeutics, Inc. | 1.86 | 2.16 | 2.23 | 1.85 | 4.77 | 0.35 | -0.29 (-13.49%) | -25.60% | 23.18% | 129.85M | 2.86 | -34.95% | 1.91 | -2.68% | F Strong Sell |
| 159 | EYPT | EyePoint Pharmaceuticals, Inc. | 1.02 | 1.00 | 1.03 | 0.95 | 2.69 | 0.81 | 0.01 (0.99%) | -34.19% | -43.02% | 127.24M | 1.47 | -30.55% | 1.61 | -36.55% | F Strong Sell |
| 160 | SVRA | Savara, Inc. | 2.12 | 2.00 | 2.32 | 2.00 | 11.96 | 0.69 | -0.23 (-9.79%) | -52.68% | -71.23% | 107.78M | 2.52 | -15.74% | 2.16 | -1.83% | F Strong Sell |
| 161 | SBBP | Strongbridge Biopharma plc - Ordinary Shares | 1.89 | 1.88 | 1.91 | 1.74 | 5.06 | 1.43 | -0.01 (-0.53%) | -9.57% | -62.05% | 102.53M | 2.69 | -29.65% | 2.44 | -22.62% | F Strong Sell |
| 162 | PHAS | PhaseBio Pharmaceuticals, Inc. | 3.31 | 3.40 | 3.64 | 3.23 | 16.65 | 2.60 | -0.09 (-2.65%) | -45.83% | -65.19% | 95.22M | 4.31 | -23.13% | 5.91 | -44.03% | F Strong Sell |
| 163 | ACRX | AcelRx Pharmaceuticals, Inc. | 1.18 | 1.26 | 1.26 | 1.11 | 4.00 | 0.70 | -0.09 (-7.09%) | -44.08% | -66.09% | 94.89M | 1.42 | -16.61% | 2.03 | -41.83% | F Strong Sell |
| 164 | CKPT | Checkpoint Therapeutics, Inc. | 1.51 | 1.50 | 1.58 | 1.34 | 5.20 | 1.05 | 0.00 (0.00%) | -12.21% | -47.20% | 83.11M | 1.80 | -15.90% | 2.15 | -29.78% | F Strong Sell |
| 165 | ELOX | Eloxx Pharmaceuticals, Inc. | 1.96 | 2.13 | 2.18 | 1.89 | 13.46 | 1.89 | -0.17 (-7.98%) | -73.37% | -83.22% | 78.63M | 3.45 | -43.21% | 5.63 | -65.16% | F Strong Sell |
| 166 | ETON | Eton Pharmaceuticals, Inc. | 4.10 | 4.07 | 4.27 | 3.96 | 10.20 | 2.50 | 0.10 (2.50%) | -43.06% | -48.75% | 73.32M | 5.48 | -25.11% | 6.20 | -33.86% | F Strong Sell |
| 167 | XERS | Xeris Pharmaceuticals, Inc. | 1.95 | 2.15 | 2.15 | 1.85 | 12.98 | 1.42 | -0.22 (-10.14%) | -72.34% | -80.58% | 73.26M | 3.87 | -49.56% | 8.11 | -75.95% | F Strong Sell |
| 168 | AKRX | Akorn, Inc. | 0.56 | 0.64 | 0.64 | 0.56 | 5.46 | 0.37 | -0.08 (-12.98%) | -62.67% | -84.06% | 70.85M | 1.11 | -49.76% | 2.95 | -81.00% | F Strong Sell |
| 169 | MNLO | Menlo Therapeutics Inc. | 2.68 | 2.65 | 2.82 | 2.40 | 8.13 | 1.87 | 0.05 (1.90%) | -42.24% | -65.86% | 65.50M | 4.10 | -34.62% | 4.57 | -41.41% | F Strong Sell |
| 170 | PTI | Proteostasis Therapeutics, Inc. | 1.14 | 1.21 | 1.26 | 1.12 | 4.72 | 0.61 | -0.08 (-6.56%) | -50.00% | -9.52% | 59.45M | 1.55 | -26.32% | 1.35 | -15.40% | F Strong Sell |
| 171 | TRVI | Trevi Therapeutics, Inc. | 3.29 | 2.19 | 6.00 | 1.95 | 10.62 | 1.33 | 1.58 (92.40%) | -12.27% | -58.30% | 58.68M | 4.51 | -27.05% | 4.79 | -31.33% | F Strong Sell |
| 172 | SYBX | Synlogic, Inc. | 1.72 | 1.84 | 1.85 | 1.63 | 10.01 | 1.35 | -0.12 (-6.52%) | -33.33% | -77.34% | 55.47M | 2.27 | -24.20% | 3.45 | -50.17% | F Strong Sell |
| 173 | CPIX | Cumberland Pharmaceuticals Inc. | 3.63 | 3.70 | 3.70 | 3.50 | 6.99 | 3.32 | 0.00 (0.00%) | -29.51% | -37.52% | 55.11M | 4.32 | -16.05% | 5.18 | -29.91% | F Strong Sell |
| 174 | ASRT | Assertio Therapeutics, Inc. | 0.65 | 0.66 | 0.68 | 0.61 | 5.76 | 0.55 | -0.03 (-4.96%) | -48.00% | -87.18% | 52.84M | 1.04 | -37.27% | 1.50 | -56.52% | F Strong Sell |
| 175 | SURF | Surface Oncology, Inc. | 1.87 | 1.91 | 1.96 | 1.86 | 5.09 | 1.15 | -0.01 (-0.53%) | -0.53% | -60.80% | 52.47M | 2.71 | -30.99% | 2.20 | -15.04% | F Strong Sell |
| 176 | MIST | Milestone Pharmaceuticals Inc. | 1.84 | 1.84 | 1.96 | 1.75 | 27.95 | 1.69 | -0.03 (-1.60%) | -88.51% | -88.03% | 45.19M | 17.33 | -89.38% | 18.52 | -90.07% | F Strong Sell |
| 177 | OPNT | Opiant Pharmaceuticals, Inc. | 9.58 | 10.31 | 10.31 | 9.32 | 18.23 | 8.05 | 0.20 (2.13%) | -33.47% | -26.98% | 40.61M | 11.59 | -17.31% | 13.50 | -29.06% | F Strong Sell |
| 178 | EYEN | Eyenovia, Inc. | 2.30 | 2.80 | 2.80 | 2.22 | 6.98 | 1.11 | -0.39 (-14.50%) | -48.66% | -61.60% | 37.82M | 3.65 | -36.98% | 3.61 | -36.30% | F Strong Sell |
| 179 | NEOS | Neos Therapeutics, Inc. | 0.75 | 0.76 | 0.79 | 0.69 | 2.75 | 0.60 | 0.00 (0.01%) | -50.33% | -71.26% | 37.31M | 1.36 | -44.71% | 1.49 | -49.55% | F Strong Sell |
| 180 | ETTX | Entasis Therapeutics Holdings Inc. | 2.64 | 2.65 | 2.76 | 2.55 | 9.25 | 1.75 | 0.03 (1.15%) | -46.88% | -60.88% | 35.09M | 4.41 | -40.10% | 5.58 | -52.69% | F Strong Sell |
| 181 | HOTH | Hoth Therapeutics, Inc. | 3.06 | 3.00 | 3.26 | 2.83 | 9.07 | 2.60 | 0.02 (0.66%) | -50.57% | -40.58% | 30.96M | 4.15 | -26.34% | 4.79 | -36.13% | F Strong Sell |
| 182 | ECOR | electroCore, Inc. | 0.95 | 0.94 | 1.19 | 0.82 | 7.18 | 0.32 | -0.26 (-21.49%) | -40.25% | -86.43% | 28.04M | 0.89 | 7.05% | 1.62 | -41.35% | F Strong Sell |
| 183 | ALNA | Allena Pharmaceuticals, Inc. | 0.96 | 1.04 | 1.05 | 0.94 | 7.00 | 0.53 | -0.04 (-3.75%) | -64.84% | -86.29% | 23.81M | 1.85 | -48.09% | 3.27 | -70.64% | F Strong Sell |
| 184 | ZOM | Zomedica Pharmaceuticals Corp. Common Shares | 0.19 | 0.21 | 0.22 | 0.18 | 0.50 | 0.12 | -0.02 (-10.86%) | -42.60% | -45.80% | 20.49M | 0.21 | -10.09% | 0.29 | -34.60% | F Strong Sell |
| 185 | ACER | Acer Therapeutics Inc. | 1.99 | 1.87 | 2.04 | 1.86 | 28.25 | 1.08 | 0.10 (5.29%) | -50.37% | -91.81% | 20.09M | 3.59 | -44.64% | 3.77 | -47.21% | F Strong Sell |
| 186 | SXTC | China SXT Pharmaceuticals, Inc. | 0.56 | 0.63 | 0.84 | 0.53 | 7.00 | 0.50 | -0.07 (-11.10%) | -31.71% | -91.79% | 15.53M | 0.86 | -34.56% | 1.56 | -64.02% | F Strong Sell |
| 187 | SBPH | Spring Bank Pharmaceuticals, Inc. | 0.93 | 1.00 | 1.04 | 0.89 | 11.00 | 0.80 | -0.03 (-3.12%) | -41.14% | -91.13% | 15.36M | 1.23 | -24.55% | 2.94 | -68.38% | F Strong Sell |
| 188 | ADIL | Adial Pharmaceuticals, Inc | 1.30 | 1.35 | 1.35 | 1.30 | 3.48 | 1.00 | -0.04 (-2.99%) | -46.06% | -62.10% | 13.62M | 1.55 | -16.38% | 1.71 | -23.83% | F Strong Sell |
| 189 | UMRX | Unum Therapeutics Inc. | 0.41 | 0.41 | 0.45 | 0.41 | 4.62 | 0.30 | -0.00 (-0.91%) | -43.07% | -90.59% | 12.35M | 0.66 | -37.48% | 1.31 | -68.81% | F Strong Sell |
| 190 | IMRN | Immuron Limited | 1.81 | 1.77 | 1.88 | 1.77 | 7.80 | 1.55 | 0.05 (2.85%) | -50.14% | -69.40% | 6.48M | 3.07 | -41.11% | 3.19 | -43.23% | F Strong Sell |
| 191 | NTEC | Intec Pharma Ltd. - Ordinary Shares | 0.20 | 0.21 | 0.21 | 0.19 | 7.99 | 0.13 | -0.02 (-8.41%) | -60.00% | -97.31% | 6.47M | 0.30 | -32.22% | 0.94 | -78.82% | F Strong Sell |
| 192 | TENX | Tenax Therapeutics, Inc. | 0.57 | 0.56 | 0.60 | 0.53 | 2.16 | 0.25 | 0.01 (2.09%) | -59.57% | -71.70% | 3.92M | 1.04 | -45.11% | 1.21 | -52.91% | F Strong Sell |
| 193 | SNES | SenesTech, Inc. | 2.07 | 2.23 | 2.23 | 2.07 | 39.00 | 1.62 | -0.11 (-5.05%) | -81.18% | -91.52% | 3.77M | 4.32 | -52.08% | 15.79 | -86.89% | F Strong Sell |
| NR | BBIO | BridgeBio Pharma, Inc. | 29.00 | 26.65 | 29.00 | 26.38 | 48.36 | 14.23 | 2.33 (8.74%) | -17.26% | 5.26% | 3.59B | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | MIRM | Mirum Pharmaceuticals, Inc. - common stock | 14.00 | 13.95 | 14.40 | 13.09 | 28.31 | 6.51 | 0.01 (0.07%) | -42.90% | 5.98% | 355.46M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | BITI | Biotie Therapies Cor | 25.80 | 26.52 | 26.52 | 25.69 | 27.96 | 12.43 | -0.71 (-2.68%) | 79.79% | 25.18% | 351.40M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | BFRA | Biofrontera AG | 7.08 | 7.07 | 7.08 | 7.07 | 18.32 | 7.07 | 0.00 (0.00%) | -31.92% | -45.12% | 158.77M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | OASM | Oasmia Pharmaceutical AB | 1.55 | 1.57 | 1.57 | 1.55 | 5.70 | 0.94 | 0.03 (1.97%) | -48.68% | -13.89% | 116.20M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | AQXP | Aquinox Pharmaceuticals, Inc. | 3.68 | 3.50 | 3.84 | 3.46 | 3.84 | 2.00 | 0.21 (6.05%) | 70.37% | 16.09% | 86.62M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | HAPP | HAPPINESS BIOTECH GROUP LTD | 3.15 | 3.00 | 3.48 | 2.87 | 6.10 | 2.44 | 0.18 (6.06%) | -30.85% | -30.00% | 78.75M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | ASNS | Arsanis, Inc. | 3.11 | 3.24 | 3.78 | 3.05 | 28.69 | 1.15 | -0.13 (-3.86%) | 34.05% | -86.33% | 45.54M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | CNSP | CNS PHARMACEUTICALS, INC. | 2.10 | 2.00 | 2.10 | 2.00 | 5.69 | 1.26 | 0.01 (0.48%) | -46.84% | -54.05% | 33.00M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | CXRX | Concordia International Corp. | 0.19 | 0.19 | 0.20 | 0.19 | 1.80 | 0.19 | 0.00 (0.00%) | -71.21% | -84.55% | 9.74M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | SGYP | Synergy Pharmaceuticals, Inc. | 0.03 | 0.06 | 0.06 | 0.03 | 2.23 | 0.03 | -0.03 (-52.00%) | -73.68% | -98.65% | 7.44M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | IPCI | Intellipharmaceutics International Inc. | 0.21 | 0.22 | 0.27 | 0.21 | 6.60 | 0.20 | -0.06 (-22.00%) | -13.22% | -96.60% | 4.60M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | GEMP | Gemphire Therapeutics Inc. | 0.30 | 0.31 | 0.34 | 0.29 | 1.49 | 0.24 | 0.00 (-0.37%) | -98.52% | -61.04% | 4.46M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | SNNA | Sienna Biopharmaceuticals, Inc. | 0.14 | 0.10 | 0.17 | 0.10 | 3.80 | 0.06 | 0.03 (34.46%) | -93.97% | -96.10% | 4.33M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | PTX | Pernix Therapeutics Holdings, Inc. | 0.21 | 0.22 | 0.24 | 0.20 | 3.30 | 0.20 | -0.01 (-4.55%) | -50.00% | -92.76% | 3.05M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | ARDM | Aradigm Corporation | 0.12 | 0.31 | 0.35 | 0.07 | 2.33 | 0.07 | -0.34 (-73.91%) | -62.50% | -90.77% | 1.83M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | ARGS | Argos Therapeutics, Inc. | 0.10 | 0.10 | 0.11 | 0.10 | 4.00 | 0.07 | 0.00 (0.00%) | -33.33% | -97.06% | 1.06M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | ORTX | Orchard Therapeutics plc | 7.53 | 7.81 | 7.86 | 7.30 | 21.64 | 5.17 | -0.06 (-0.79%) | -45.24% | -57.89% | 724.31M | 10.82 | -30.38% | 12.62 | -40.35% | NR Not Rated |
| NR | MRNA | Moderna, Inc. | 29.95 | 30.60 | 30.98 | 29.20 | 36.00 | 11.54 | -0.53 (-1.74%) | 53.12% | 47.17% | 9.85B | 23.89 | 25.34% | 18.27 | 63.90% | NR Not Rated |
| NR | HOOK | HOOKIPA Pharma Inc. | 8.25 | 8.30 | 8.46 | 7.83 | 14.76 | 5.80 | -0.10 (-1.20%) | -32.54% | -41.07% | 180.06M | 10.82 | -23.72% | 8.83 | -6.58% | NR Not Rated |
| NR | SNDL | Sundial Growers Inc. | 0.64 | 0.57 | 0.75 | 0.51 | 13.22 | 0.51 | -0.31 (-32.63%) | -78.74% | -92.45% | 53.64M | N/A | N/A% | N/A | N/A% | NR Not Rated |
| NR | OGI | Organigram Holdings Inc. | 2.00 | 2.00 | 2.10 | 1.94 | 8.44 | 1.41 | -0.03 (-1.48%) | -18.37% | -70.37% | 346.16M | 2.23 | -10.27% | 3.65 | -45.15% | NR Not Rated |
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